Which 3 characters die in Madame Web?

Warning – The rest of this article contains spoilers for Madame Web

Two character deaths lay the groundwork for the plot of Madame Web.

To begin the film, Cassie’s mother, Constance, is in the Peruvian jungle researching spiders alongside lead antagonist Ezekiel Sims (Tahar Rahim).

This is a flashback scene during 1973, the moment infamously referenced in the trailer with this line by Cassie, “He was in the Amazon with my mom when she was researching spiders right before she died.”

Ironically, this snippet of dialogue is not delivered in Madame Web, but her mother (pregnant with Cassie) does die during labor following a fatal gunshot wound at the hands of Ezekiel.

Photo of Dakota as Madame Web

It is later revealed in the film that Cassie would have been born with a life-altering disease, leading Constance to travel to the Amazon rainforest to find a cure.

The opening scene connects Cassie to the Amazonian Spider-People, as Constance is bitten by a powerful spider before death, thus later giving Cassie her psychic abilities and (without her realizing it) extending her life expectancy.

The other death that generates much of the film’s unraveling plot is that of Ezekiel Sims. Early in the movie, Ezekiel dreams of his death at the hands of three Spider-Women (Sweeney, Merced, and O’Connor’s characters).

This puts him on a villainous path of tracking down the three teenage girls to end their lives before his doomed fate becomes a reality.

As the plot unfolds, Cassie attempts to save the three girls because she sees the future of Ezekiel succeeding in killing all three of them. During the final battle, Cassie is ultimately the one who ends Ezekiel’s life, putting an end to his hunt.

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